The William Lindsey House is a historic house located at 373 North Main Street in Fall River, Massachusetts. It was designed by Rhode Island architect Russell Warren in 1844 for William Lindsey, a local merchant. It is one of seven extant monumental temple-fronted Greek Revival houses in Fall River, along with the John Mace Smith House next door. It is a 2+1⁄2-story wood-frame structure, five bays wide, with a hip roof topped by an octagonal cupola. The Greek temple front consists of a fully pedimented gable and entablature supported by four fluted Corinthian columns.